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General information. Nexavar is a cancer medication that interferes with the growth and spread of cancer cells in the body. Sorafenib stops or slows the growth of cancer cells (tumors). It also works by slowing the growth of new blood vessels within the tumor. Nexavar may also be used to treat a certain type of thyroid cancer (differentiated thyroid carcinoma).
Contraindications. Before taking sorafenib, tell your doctor or pharmacist if you are allergic to it. You should not use Nexavar if you have squamous cell lung cancer and you are being treated with carboplatin (Paraplatin) and paclitaxel (Onxol, Taxol, Abraxane). Do not use Nexavar if you have kidney or liver problems other than cancer; lung cancer; a bleeding or blood clotting disorder such as hemophilia; high blood pressure (hypertension), heart disease, slow heartbeats, congestive heart failure, chest pain; a personal or family history of Long QT syndrome; a history of stroke or heart attack.
Precautions. Nexavar can cause heart problems. Stop taking this medicine and call your doctor at once if you have chest pain and severe dizziness, fainting, sweating, or feeling short of breath. Nexavar can also cause severe bleeding. Call your doctor if you have blood in your urine or stools, abnormal vaginal bleeding, severe stomach pain, coughing up blood, or any bleeding that will not stop. Do not have immunizations/vaccinations without the consent of your doctor and avoid contact with people who have recently received oral polio vaccine or flu vaccine inhaled through the nose. To lower the chance of getting cut, bruised or injured, use caution with sharp objects like safety razors and nail cutters, and avoid activities such as contact sports. Women who are pregnant must not take this medication as it can be absorbed through the skin and lungs and may harm an unborn baby.
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